Circadian cortisol profiles, anxiety and depressive symptomatology, and body mass index in a clinical population of obese children.

Circadian cortisol profiles, anxiety and depressive symptomatology, and body mass index in a clinical population of obese children. Pervanidou P1, Bastaki D, Chouliaras G, Papanikolaou K, Laios E, Kanaka-Gantenbein C, Chrousos GP. Stress. 2013 Jan;16(1):34-43.

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Obesity is highly co-morbid with anxiety and/or depression in children, conditions that may further worsen the metabolic and cardiovascular risks for obese individuals. Dysregulation of the hypothalamic-pituitary-adrenal axis is involved in the pathophysiology of anxiety disorders, depression, and obesity, and diverse cortisol concentrations may be found in obese children, depending on their degree of psychological distress. The aim of this study was to examine cortisol profiles among obese children with or without symptoms of anxiety and depression.

 Stress. 2013 Jan;16(1):34-43.

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